Insulin-induced improvement of postischemic recovery is abolished by inhibition of protein kinase C in rat heart.

Abstract

OBJECTIVE We demonstrated earlier that postischemic addition of insulin improves recovery of function in isolated rat heart by phosphatidylinositol 3-kinase. Activation of phosphatidylinositol 3-kinase before ischemia improves recovery of the heart after ischemia through protein kinase C. We tested whether protein kinase C activation is required for the… (More)

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@article{FischerRasokat2003InsulininducedIO, title={Insulin-induced improvement of postischemic recovery is abolished by inhibition of protein kinase C in rat heart.}, author={Ulrich Fischer-Rasokat and Torsten Doenst}, journal={The Journal of thoracic and cardiovascular surgery}, year={2003}, volume={126 6}, pages={1806-12} }