Insulin increases serum leptin concentrations in children and adolescents with newly diagnosed Type I diabetes mellitus with and without ketoacidosis

@article{Flck1999InsulinIS,
  title={Insulin increases serum leptin concentrations in children and adolescents with newly diagnosed Type I diabetes mellitus with and without ketoacidosis},
  author={Christa E Fl{\"u}ck and Britta Kuhlmann and Primus E. Mullis},
  journal={Diabetologia},
  year={1999},
  volume={42},
  pages={1067-1070}
}
Aims/hypothesis. The aims of this study were to analyse the changes of serum leptin in newly diagnosed children and adolescents with Type I (insulin-dependent) diabetes mellitus after insulin treatment and to examine the possible impact of ketoacidosis on these changes. Methods. Baseline serum leptin concentrations were measured in 28 newly diagnosed Type I diabetic patients [age 8.75 ± 4.05 years (means ± SD); BMI 15.79 ± 2.47 kg/m2; HbA1 c 11.3 ± 1.9 %] with (n = 18) and without (n = 10… CONTINUE READING
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