Insulin exerts direct effects on carcinogenic transformation of human endometrial organotypic cultures.

Abstract

Epidemiological studies suggest an association between elevated insulin levels and endometrial cancer. We studied the effects of insulin on normal endometrial cell proliferation with cytotoxicity assays. Organotypic cultures were used to determine the effects of insulin on the development of malignant histological features and anchorage independent growth… (More)
DOI: 10.3109/07357907.2013.877479

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