Insulin dissociates hepatic glucose cycling and glucagon-induced thermogenesis in man.

@article{CallesEscandn1994InsulinDH,
  title={Insulin dissociates hepatic glucose cycling and glucagon-induced thermogenesis in man.},
  author={Jorge Calles-Escand{\'o}n},
  journal={Metabolism: clinical and experimental},
  year={1994},
  volume={43 8},
  pages={1000-5}
}
The quantitative contribution of hepatic glucose cycling to basal and glucagon-stimulated thermogenesis was investigated in seven normal healthy volunteers in whom energy expenditure (EE) was measured simultaneously with indirect calorimetry. Primed-constant infusions of 2-(2H1)-glucose and 6-6'-(2H2)-glucose were used to calculate hepatic glucose cycling. Gas chromatography/mass spectrometry was used to measure the plasma enrichment of isotopes. In response to hyperglucagonemia, basal EE… CONTINUE READING

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