Insulin catalyzes the curcumin-induced wound healing: An in vitro model for gingival repair

@inproceedings{Singh2012InsulinCT,
  title={Insulin catalyzes the curcumin-induced wound healing: An in vitro model for gingival repair},
  author={Neetu Singh and Vishal Ranjan and Deeba Zaidi and Hari Shyam and Aparna Singh and Divya Lodha and Ramesh Sharma and Umesh Pratap Verma and J. N. Dixit and Anil Kumar Balapure},
  booktitle={Indian journal of pharmacology},
  year={2012}
}
OBJECTIVES Human gingival fibroblasts (hGFs) play a major role in the maintenance and repair of gingival connective tissue. The mitogen insulin with IGFs etc. synergizes in facilitating wound repair. Although curcumin (CUR) and insulin regulate apoptosis, their impact as a combination on hGF in wound repair remains unknown. Our study consists of: 1) analysis of insulin-mediated mitogenesis on CUR-treated hGF cells, and 2) development of an in vitro model of wound healing. MATERIALS AND… CONTINUE READING

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