Insulin autoimmune syndrome (Hirata disease): clinical features and epidemiology in Japan.

@article{Uchigata1994InsulinAS,
  title={Insulin autoimmune syndrome (Hirata disease): clinical features and epidemiology in Japan.},
  author={Yasuko Uchigata and Yoko S Eguchi and S Takayama-Hasumi and Yasue Omori},
  journal={Diabetes research and clinical practice},
  year={1994},
  volume={22 2-3},
  pages={89-94}
}
Since Hirata et al. first reported a patient with insulin autoimmune syndrome in 1970, 197 cases have been reported in Japan as of December, 1992. The clinical profiles of these 197 cases were as follows; the peak age at onset was 60-69 years and peak duration of hypoglycemic attacks was more than 1 and less than 3 months. There was no gender difference in the peak age of onset or duration of hypoglycemic attacks. Approximately 82% of the IAS patients had spontaneous remission without any… CONTINUE READING
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