Insulin aspart improves meal time glycaemic control in patients with Type 2 diabetes: a randomized, stratified, double‐blind and cross‐over trial
@article{Perriello2005InsulinAI, title={Insulin aspart improves meal time glycaemic control in patients with Type 2 diabetes: a randomized, stratified, double‐blind and cross‐over trial}, author={G. Perriello and S. Pampanelli and F. Porcellati and A. Avogaro and E. Bosi and G. Petrella and S. Squatrito and S. Furneri and G. Marra and L. Vitali and M. Previti and D. Cucinotta}, journal={Diabetic Medicine}, year={2005}, volume={22} }
Aims This randomized, multi‐centre, double‐blind, stratified, two period, cross‐over trial was undertaken to assess the pharmacokinetics and pharmacodynamics of insulin aspart injected immediately before compared with regular human insulin injected 30 min before a Mediterranean‐style meal in 37 (23 M, 14 F) patients with Type 2 diabetes.
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References
SHOWING 1-10 OF 22 REFERENCES
Improved postprandial glycemic control with insulin aspart. A randomized double-blind cross-over trial in type 1 diabetes.
- Medicine
- Diabetes care
- 1999
- 171
Improved glycemic control with insulin aspart: a multicenter randomized double-blind crossover trial in type 1 diabetic patients. UK Insulin Aspart Study Group.
- Medicine
- Diabetes care
- 1998
- 227
Improved postprandial glycaemic controls with insulin Aspart in type 2 diabetic patients treated with insulin
- Medicine
- Acta Diabetologica
- 2000
- 111
Mealtime glucose regulation in type 2 diabetes.
- Medicine
- International journal of clinical practice
- 2001
- 13
Comparison of Bedtime Insulin Regimens in Patients with Type 2 Diabetes Mellitus
- Medicine
- Annals of Internal Medicine
- 1999
- 474
Physiological insulin replacement in type 1 diabetes mellitus.
- Medicine
- Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
- 2001
- 52
Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study.
- Medicine
- Diabetes research and clinical practice
- 1995
- 2,254
Comparison of insulin regimens in patients with non-insulin-dependent diabetes mellitus.
- Medicine
- The New England journal of medicine
- 1992
- 275