Insulin and heparin suppress superoxide production in diabetic rat glomeruli stimulated with low-density lipoprotein.

Abstract

Patients with diabetic nephropathy frequently show increased levels of circulating low-density lipoprotein (LDL) and oxidized LDL, which have been reported to be related to the generation of oxygen-free radicals. In the present study, we evaluated the effects of insulin and heparin on the superoxide production of glomeruli, which were isolated from rats… (More)

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@article{Chen2001InsulinAH, title={Insulin and heparin suppress superoxide production in diabetic rat glomeruli stimulated with low-density lipoprotein.}, author={H. C. Chen and J. Y. Guh and S. J. Shin and J. H. Tsai and Yurong Lai}, journal={Kidney international. Supplement}, year={2001}, volume={78}, pages={S124-7} }