Insulin and glucagon secretion in the rat: effects of gastrin releasing peptide.

@article{Pettersson1988InsulinAG,
  title={Insulin and glucagon secretion in the rat: effects of gastrin releasing peptide.},
  author={Magnus Pettersson and Bo Ahr{\'e}n},
  journal={Neuropeptides},
  year={1988},
  volume={12 3},
  pages={159-63}
}
Immunoreactive gastrin releasing peptide (GRP) has been shown to occur in intrapancreatic nerve fibers, and to be released from the perfused porcine pancreas during electrical vagal activation. Hence, it could be anticipated that GRP may be of functional importance for the neural control of islet hormone secretion. Therefore, we investigated the effects of intravenous infusion of GRP on basal and stimulated insulin and glucagon secretion in vivo in the rat. We found that GRP, at 4.3 or 17 pmol… CONTINUE READING