Insulin and atherosclerosis: how are they related?

@article{Monnier2013InsulinAA,
  title={Insulin and atherosclerosis: how are they related?},
  author={Louis Monnier and Markolf Hanefeld and Oliver Schnell and Claude Colette and David R. Owens},
  journal={Diabetes & metabolism},
  year={2013},
  volume={39 2},
  pages={111-7}
}
The relationship between insulin and atherosclerosis is complex. People with type 2 diabetes are affected by three main glycaemic disorders: chronic hyperglycaemia; glycaemic variability; and iatrogenic hypoglycaemia. In addition to this triumvirate, the diabetic condition is characterized by lipid disorders, chronic low-grade inflammation and activation of oxidative stress. All these associated disorders reflect the insulin-resistant nature of type 2 diabetes and contribute to the development… CONTINUE READING

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The contribution of glucose variability to asymptomatic hypoglycemia in persons with type 2 diabetes

L Monnier, A Wojtuscizyn, C Colette, D Owens
Diabetes Technol Ther • 2012

cose oscillations , more than constant high glucose , induce p 53 activation and a metabolic memory in human endothelial cells

A Ceriello, K Esposito, +3 authors R Testa
Diabetologia • 2011

Regu - lation of oxidative stress by glycaemic control : evidence for an independent inhibitory effect of insulin therapy

P Dandona, A Chaudhuri, H Ghanim, P Mohanty
Diabetologia • 2010

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