Insulin and atherosclerosis: how are they related?

  title={Insulin and atherosclerosis: how are they related?},
  author={Louis Monnier and Markolf Hanefeld and Oliver Schnell and Claude Colette and David R. Owens},
  journal={Diabetes & metabolism},
  volume={39 2},
The relationship between insulin and atherosclerosis is complex. People with type 2 diabetes are affected by three main glycaemic disorders: chronic hyperglycaemia; glycaemic variability; and iatrogenic hypoglycaemia. In addition to this triumvirate, the diabetic condition is characterized by lipid disorders, chronic low-grade inflammation and activation of oxidative stress. All these associated disorders reflect the insulin-resistant nature of type 2 diabetes and contribute to the development… CONTINUE READING

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