Insulin and IGF-I stimulate phosphorylation of their respective receptors in intact neuronal and glial cells in primary culture

Previous studies have shown that insulin and IGF-I bind to their respective receptors and stimulate autophosphorylation of the receptor β subunits in detergent extracts of neuronal and glial cells. In the present study, intact neuronal and glial cells in primary culture have been utilized to characterize insulin- and IGF-I-stimulated phosphorylation of… CONTINUE READING