Insulin acts as an embryonic growth factor for Drosophila neural cells.

@article{Pimentel1996InsulinAA,
  title={Insulin acts as an embryonic growth factor for Drosophila neural cells.},
  author={Bel{\'e}n Pimentel and Enrique J de la Rosa and Flora de Pablo},
  journal={Biochemical and biophysical research communications},
  year={1996},
  volume={226 3},
  pages={855-61}
}
The isolation of the Drosophila insulin receptor gene and the recent analysis of loss of function mutants have clearly implicated insulin signalling in embryonic nervous system development. Here we study the presence of insulin in the embryo and we characterize the cellular processes affected by insulin in embryonic neural cells. We find that 7.5% of the cells in the 15-18 h Drosophila embryo contain insulin immunoreactivity by flow cytometry. In the embryonic-derived cell line Schneider 1, we… CONTINUE READING