Insulin-Like Growth Factor (IGF)-I Gene Deletion

  title={Insulin-Like Growth Factor (IGF)-I Gene Deletion},
  author={Cecilia Camacho-H{\"u}bner and Katie A. Woods and Adrian J. L. Clark and Martin O. Savage},
  journal={Reviews in Endocrine and Metabolic Disorders},
Insulin-like growth factor-I (IGF-I) deficiency is a clinical condition usually associated with severe post-natal growth failure and characterized by a combination of auxological, clinical, and metabolic abnormalities caused by decreased IGF-I biologic action [1–3]. IGF-I deficiency can result from a defect in the IGF-I gene or in its promoter or can be… CONTINUE READING