Insulin Induction of Protein Kinase Cα Expression Is Independent of Insulin Receptor Tyr1162/1163 Residues and Involves Mitogen-Activated Protein Kinase Kinase 1 and Sustained Activation of Nuclear p44MAPK.

Abstract

We examined the effect of insulin on protein kinase Ca (PKCa) expression and the implication of the mitogen-activated protein kinase kinase 1 mitogen-activated protein kinase (MAPK) pathway in this effect. PKCa expression was measured by quantitative RT-PCR and Western blotting using Chinese hamster ovary (CHO) cells overexpressing human insulin receptors… (More)
DOI: 10.1210/endo.139.7.6094

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@article{Antoine1998InsulinIO, title={Insulin Induction of Protein Kinase Cα Expression Is Independent of Insulin Receptor Tyr1162/1163 Residues and Involves Mitogen-Activated Protein Kinase Kinase 1 and Sustained Activation of Nuclear p44MAPK.}, author={Pierre Jacques Antoine and France Bertrand and Martine Auclair and Jocelyne Magr{\'e} and Jacqueline Capeau and Gise le Cherqui}, journal={Endocrinology}, year={1998}, volume={139 7}, pages={3133-3142} }