Insulin Analogs—Is There a Compelling Case to Use Them? No!

@inproceedings{Davidson2014InsulinAT,
  title={Insulin Analogs—Is There a Compelling Case to Use Them? No!},
  author={Mayer B. Davidson},
  booktitle={Diabetes care},
  year={2014}
}
The availability of insulin analogs has offered insulin replacement strategies that are proposed to more closely mimic normal human physiology. Specifically, there are a considerable number of reports demonstrating that prandial insulin analogs (lispro, aspart, glulisine) have pharmacokinetic and pharmacodynamic profiles closer to normal, with resulting faster onset and offset of insulin effect when compared with regular human insulin. In addition, basal insulin analogs (glargine, detemir) have… CONTINUE READING
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