Insulin/insulin-like growth factor I and other epigenetic modulators of myelin basic protein expression in isolated oligodendrocyte progenitor cells.

Abstract

The expression of myelin basic protein by the oligodendrocyte is an integral event in the maturation of central nervous system function. Although much is known concerning the various myelin basic protein species, their temporal expression, and processing of RNA transcripts, little is known about the epigenetic factors responsible for the regulation of… (More)

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