Insulin, leptin, IGF-I and insulin-dependent protein concentrations after insulin-sensitizing therapy in obese women with polycystic ovary syndrome.

@article{Kowalska2001InsulinLI,
  title={Insulin, leptin, IGF-I and insulin-dependent protein concentrations after insulin-sensitizing therapy in obese women with polycystic ovary syndrome.},
  author={Irina Kowalska and Maciej Kinalski and Marek Strączkowski and S Wolczyski and I. Kinalska},
  journal={European journal of endocrinology},
  year={2001},
  volume={144 5},
  pages={509-15}
}
OBJECTIVE To determine the clinical, hormonal and biochemical effect of 4-5 months of insulin-sensitizing therapy (hypocaloric diet+metformin) in obese patients with polycystic ovary syndrome (PCOS). DESIGN Prospective study. METHODS Twenty-three obese patients with PCOS, 19 obese patients without menstrual disturbances and 11 healthy control women were recruited from the Department of Endocrinology and Endocrine Gynecology, Medical Academy, Bialystok, Poland. Obese patients received 500 mg… CONTINUE READING