Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster.

Abstract

The genomic binding sites of Polycomb group (PcG) complexes have been found to cluster, forming Polycomb "bodies" or foci in mammalian or fly nuclei. These associations are thought to be driven by interactions between PcG complexes and result in enhanced repression. Here, we show that a Polycomb response element (PRE) with strong PcG binding and repressive… (More)
DOI: 10.1128/MCB.00849-10

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Cite this paper

@article{Li2011InsulatorsNP, title={Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster.}, author={Hua-Bing Li and Martin M{\"{u}ller and Ilham Anne Bahechar and Olga Kyrchanova and Katsuhito Ohno and Pavel Georgiev and Vincenzo Pirrotta}, journal={Molecular and cellular biology}, year={2011}, volume={31 4}, pages={616-25} }