Insular and anaplastic carcinoma of the thyroid: a 45-year comparative study at a single institution and a review of the significance of p53 and p21.

@article{Lam2000InsularAA,
  title={Insular and anaplastic carcinoma of the thyroid: a 45-year comparative study at a single institution and a review of the significance of p53 and p21.},
  author={K. Y. Lam and Chung Yau Lo and Ka Wah Chan and Koon Yat Wan},
  journal={Annals of surgery},
  year={2000},
  volume={231 3},
  pages={329-38}
}
OBJECTIVE To analyze the clinicopathologic features of a large cohort of patients with insular or anaplastic carcinomas treated at a single institution. SUMMARY BACKGROUND DATA Insular and anaplastic carcinomas of the thyroid, although uncommon, have more aggressive clinical behavior than well-differentiated carcinomas of the thyroid. In the literature, the incidence and features of these carcinomas have not been fully characterized. METHODS The authors reclassified 740 primary thyroid… CONTINUE READING