Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock

@inproceedings{Taccone2010InsufficientC,
  title={Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock},
  author={Fabio Silvio Taccone and Pierre F. Laterre and Thierry L Dugernier and Herbert D. Spapen and Isabelle Karine Delattre and Xavier Wittebole and Daniel De Backer and Brice Layeux and Pierre E Wallemacq and Jean-Louis Vincent and Fr{\'e}d{\'e}rique Jacobs},
  booktitle={Critical care},
  year={2010}
}
INTRODUCTION Altered pharmacokinetics (PK) in critically ill patients can result in insufficient serum β-lactam concentrations when standard dosages are administered. Previous studies on β-lactam PK have generally excluded the most severely ill patients, or were conducted during the steady-state period of treatment. The aim of our study was to determine whether the first dose of piperacillin-tazobactam, ceftazidime, cefepime, and meropenem would result in adequate serum drug concentrations in… CONTINUE READING
BETA
Highly Influential
This paper has highly influenced 10 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Highly Cited
This paper has 145 citations. REVIEW CITATIONS
Tweets
This paper has been referenced on Twitter 10 times. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-10 OF 106 CITATIONS, ESTIMATED 58% COVERAGE

146 Citations

01020'01'04'08'12'16
Citations per Year
Semantic Scholar estimates that this publication has 146 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-10 OF 52 REFERENCES

Similar Papers

Loading similar papers…