Instantaneous force-velocity-length relationship in diaphragmatic sarcomere.

@article{Coirault1997InstantaneousFR,
  title={Instantaneous force-velocity-length relationship in diaphragmatic sarcomere.},
  author={Catherine Coirault and Denis Chemla and J. C. Pourny and Francine Lambert and Yves Lecarpentier},
  journal={Journal of applied physiology},
  year={1997},
  volume={82 2},
  pages={
          404-12
        }
}
The simultaneous analysis of muscle force, length, velocity, and time has been shown to precisely characterize the mechanical performance of isolated striated muscle. We tested the hypothesis that the three-dimensional force-velocity-length relationship reflects mechanical properties of sarcomeres. In hamster diaphragm strips, instantaneous sarcomere length (SL) and muscle length were simultaneously measured during afterloaded twitches. SL was measured by means of laser diffraction. We also… 
View on PubMed
journals.physiology.org
5 Citations
Background Citations
4

Figures and Tables from this paper

5 Citations

Citation Type

Citation Type

Mechanics and energetics of myosin molecular motors from nonpregnant human myometrium.
TLDR
Low CB attachment and detachment rate constants made it possible to generate normal CB unitary force and normal muscle tension in NPHM, even though it contracted extremely slowly compared with other muscles.
Nonisometric behavior of fascicles during isometric contractions of a human muscle.
TLDR
It can be concluded that, in isometric contractions of a human muscle, mechanical work, some of which is absorbed by the tendinous tissue, is generated by the shortening of muscle fibers and that ultrasonography can be used to determine the stiffness and Young's modulus for human tendons.
contractions of a human muscle Nonisometric behavior of fascicles during isometric
TLDR
This article cites€23 articles, 11 of which you can access for free at: http://jap.physiology.org/content/85/4/1230.full#ref-list-1.
Diaphragm abnormalities in heart failure and aging: mechanisms and integration of cardiovascular and respiratory pathophysiology
TLDR
Exercise-based rehabilitation combined with pharmacological therapies targeting the pathways reviewed herein hold promise to treat diaphragm abnormalities and inspiratory muscle dysfunction in CHF and aging.
Effect of the biceps Brachii tendon on elbow flexor force steadiness in men and women
TLDR
The aim of the study was to establish an experimental procedure and establish a baseline for the design of a systematic literature review of this kind of Muscle and Tendon Properties at rest study.

References

SHOWING 1-10 OF 34 REFERENCES
Real-time kinetics of sarcomere relaxation by laser diffraction.
TLDR
The time course of sarcomere relaxation appeared to be progressively delayed when the total load increased from preload only up to "isometric" load, and the relative predominance of both the time course and the amplitude of these two phases depended upon the level of total load.
Mechanical determinants of isotonic relaxation in isolated diaphragm muscle.
TLDR
It is demonstrated that in isolated diaphragm muscle, delta L is the main determinant of +dL/dtmax over a wide range of loads and under various experimental conditions, independent of ESL and initial muscle length and independent of the load imposed on the muscle during the lengthening process.
Sarcomere relaxation in hamster diaphragm muscle.
TLDR
The results support the role played by sarcomere length in regulating the diaphragm muscle-lengthening rate but not the rate of tension decline, and support the preload-to-afterload relationship.
Contraction, relaxation, and economy of force generation in isolated human diaphragm muscle.
TLDR
Contraction, relaxation, and energetics of normal human diaphragm strips were investigated over the whole load continuum in both twitch and tetanus modes, and the G curvature of the P-V hyperbola and maximum mechanical efficiency were significantly higher in tetanus than in twitch.
Isometric relaxation of isolated diaphragm muscle: influence of load, length, time, and stimulation.
TLDR
In muscle isometrically relaxing at initial muscle length, peak isometric relaxation rate was mainly determined by afterload and was highly dependent on the level of activation and was independent of preload and afterload, whereas in muscle isometric relaxed at end-shortening length, the rate of tension decay differed markedly depending on stimulation conditions.
Force-length relation of isometric sarcomeres in fixed-end tetani.
TLDR
To test this possibility, single frog semitendinosus fibers were tetanized under fixed-end conditions and contained sarcomeres that, except for some initial shortening during the early part of the tetanus, remained isometric.
Effect of active pre‐shortening on isometric and isotonic performance of single frog muscle fibres.
TLDR
It is found that active preshortening reduced isometric force considerably, thereby confirming earlier work of others, and Velocity of shortening appeared to be much more sensitive to previous shortening than isometricforce.
The effect on tension of non‐uniform distribution of length changes applied to frog muscle fibres.
TLDR
Observation of internal movement during the raised tension after a lengthening contradicts theories involving ‘locked on’ bridges and an explanation for the extra tension in terms of non‐uniformity of sarcomeres is proposed.
Differences in maximum velocity of shortening along single muscle fibres of the frog.
TLDR
The results support the view that the kinetic properties of the myofilament system differ from one region to another along the length of a muscle fibre.
Mechanics of human quadriceps muscle.
TLDR
In human quadriceps muscles, contractility can be defined as the time- and initial length-invariant part of a three-dimensional P-V-L relationship, consistent with an increase in economy of force generation in tetanus contractions compared with that in twitches.
...
1
2
3
4
...