Instable osmoreceptors and deficient thirst in hypothalamic hypopituitarism


A unique abnormality of osmoreceptors is reported in a child with hypothalamic hypopituitarism. Anterior pituitary testing revealed deficiency of GH, TSH and ACTH. The clinical course was characterized by fluctuation between dehydration of diabetes insipidus and coma of water intoxication. Plasma/Urine osmolality ranged from 263/110 mOsm/kg to 325/187 mOsm… (More)
DOI: 10.1203/00006450-198101000-00063


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@article{Hochberg1981InstableOA, title={Instable osmoreceptors and deficient thirst in hypothalamic hypopituitarism}, author={Ze’ev Hochberg and Robert A Richman and Rivka Kauli}, journal={Pediatric Research}, year={1981}, volume={15}, pages={81-81} }