Instability of ventilatory control in patients with obstructive sleep apnea.

@article{Hudgel1998InstabilityOV,
  title={Instability of ventilatory control in patients with obstructive sleep apnea.},
  author={David W Hudgel and Elizabeth A. Gordon and Sukalya Thanakitcharu and Eugene N. Bruce},
  journal={American journal of respiratory and critical care medicine},
  year={1998},
  volume={158 4},
  pages={1142-9}
}
Because of the oscillatory pattern of upper airway resistance and breathing during sleep in patients with obstructive sleep apnea (OSA), we hypothesized that OSA patients have an underlying instability of ventilatory drive to inspiratory muscles. To assess the stability of ventilatory drive in OSA patients and controls, we used the pseudorandom binary stimulation (PRBS) test and examined the closed- and open-loop responses to hyperoxic hypercapnia. The closed-loop response is produced by… CONTINUE READING
47 Citations
25 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 47 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Factors related to sleep apnea syndrome in sleep clinic patients

  • Dealberto, M.-J, C. Ferber, L. Garma, P. Lemoine, A. Alperovich
  • Chest
  • 1994
1 Excerpt

Similar Papers

Loading similar papers…