Instability of clonality in gastric lymphoid infiltrates: a study with emphasis on serial biopsies.

@article{Lo2005InstabilityOC,
  title={Instability of clonality in gastric lymphoid infiltrates: a study with emphasis on serial biopsies.},
  author={William Y F Lo and Jackson Y. W. Li and Yiu K. Chan and Lawrence Siu Wing Lai and Y. W. Yeung and Stephen Tsui-Hoi Lo and Wilson Man-shan Tsui and Chi Ng},
  journal={The American journal of surgical pathology},
  year={2005},
  volume={29 12},
  pages={
          1582-92
        }
}
The evolution of low-grade B-cell mucosa-associated lymphoid-tissue (MALT) lymphoma of the stomach is a multistage process, reflected in the histologic continuum from Helicobacter pylori-chronic gastritis, to low-grade and high-grade lymphoma. Interestingly, in daily gastric biopsy sign-out, the authors observed that some biopsies showed monoclonality on polymerase chain reaction (PCR) even though there were no definite histologic features of malignancy and vice versa. To address the question… CONTINUE READING
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