Instability of Repetitive Units of Foreign Centromeric Satellite DNA in Transgenic Mice and Transfected Cells

@article{Suchkova2004InstabilityOR,
  title={Instability of Repetitive Units of Foreign Centromeric Satellite DNA in Transgenic Mice and Transfected Cells},
  author={I. O. Suchkova and N. A. Slominska and Maria E Kustova and Tatjana Baranova and Valery I Golubkov and Alexander V. Sorokin and Vadim B. Vasilyev and Eugene L Patkin},
  journal={Russian Journal of Genetics},
  year={2004},
  volume={40},
  pages={843-852}
}
Cytologically detectable instability of centromeric satellite DNA may cause hereditary disorders in human. To study the mechanisms of such instability, two transgenic mouse lines and 11 clones of transfected F9 mouse embryonic teratocarcinoma cells were obtained with the 3.8-kb repetitive unit (Sat) of Bos taurus satellite DNA IV. Intergeneration and… CONTINUE READING