Instability of GGL domain-containing RGS proteins in mice lacking the G protein-subunit G 5

@inproceedings{Chen2003InstabilityOG,
  title={Instability of GGL domain-containing RGS proteins in mice lacking the G protein-subunit G 5},
  author={C Chen and Pamela Eversole-Cire and Haikun Zhang and Valeria Mancino and Y Chen and Wei He and Theodore G Wensel and Melvin I. Simon},
  year={2003}
}
RGS (regulator of G protein signaling) proteins containing the G protein -like (GGL) domain (RGS6, RGS7, RGS9, and RGS11) interact with the fifth member of the G protein -subunit family, G 5. This interaction is necessary for the stability of both the RGS protein and for G 5. Consistent with this notion, we have found that elevation of RGS9-1 mRNA levels by… CONTINUE READING