Instabilities in the transient response of muscle.

@article{Vilfan2003InstabilitiesIT,
  title={Instabilities in the transient response of muscle.},
  author={Andrej Vilfan and Thomas Duke},
  journal={Biophysical journal},
  year={2003},
  volume={85 2},
  pages={818-27}
}
We investigate the isometric transient response of muscle using a quantitative stochastic model of the actomyosin cycle based on the swinging lever-arm hypothesis. We first consider a single pair of filaments, and show that when values of parameters such as the lever-arm displacement and the cross-bridge elasticity are chosen to provide effective energy transduction, the T(2) curve (the tension recovered immediately after a step displacement) displays a region of negative slope. If filament… CONTINUE READING
Highly Cited
This paper has 33 citations. REVIEW CITATIONS
17 Citations
5 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

References

Publications referenced by this paper.
Showing 1-5 of 5 references

The heat of shortening and dynamic constants of muscle

  • A. V. Hill
  • Am . J . Physiol
  • 1939
1 Excerpt

Similar Papers

Loading similar papers…