Insomnia medication: do published studies reflect the complete picture of efficacy and safety?

@article{Mattila2011InsomniaMD,
  title={Insomnia medication: do published studies reflect the complete picture of efficacy and safety?},
  author={Taina K. Mattila and Violeta Stoyanova and Andr{\'e} J A Elferink and Christine Gispen-de Wied and Anthonius de Boer and Tamar D Wohlfarth},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={2011},
  volume={21 7},
  pages={500-7}
}
Selective publication can have a deleterious effect on evidence based medicine, health policy decision making and treatment guidelines. Using the European Public Assessment Reports (EPARs) as reference, this study examined selective publication and selective reporting of efficacy and safety of insomnia medication. EPARs of with three insomnia medications were used to identify all clinical trials that were performed between 1998 and 2007 for the purpose of registration in the EU. The matching… CONTINUE READING
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