Insights on the interaction of met-enkephalin with negatively charged membranes--an infrared and solid-state NMR spectroscopic study.

@article{Marcotte2004InsightsOT,
  title={Insights on the interaction of met-enkephalin with negatively charged membranes--an infrared and solid-state NMR spectroscopic study.},
  author={Isabelle Marcotte and Marise Ouellet and Mich{\`e}le Auger},
  journal={Chemistry and physics of lipids},
  year={2004},
  volume={127 2},
  pages={175-87}
}
Enkephalins are pentapeptides found in the human nervous system, where they are involved in the relief of pain. The interaction of these neuropeptides with the nerve cell membranes would be a key-step in the receptor binding. We have used both Fourier-transform infrared and solid-state NMR spectroscopies to shed light on the interactions responsible for the association of enkephalins with negatively charged membranes. More specifically, we have investigated the interaction of methionine… CONTINUE READING