Insights on the functional interactions between miRNAs and copy number variations in the aging brain


MicroRNAs (miRNAs) are regulatory genetic elements that coordinate the expression of thousands of genes and play important roles in brain aging and neurodegeneration. DNA polymorphisms affecting miRNA biogenesis, dosage, and gene targeting may represent potentially functional variants. The consequences of single nucleotide polymorphisms affecting miRNA… (More)
DOI: 10.3389/fnmol.2013.00032


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Citations per Year

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