Insights on a putative aminoacyl-tRNA-protein transferase of Leishmania major

@inproceedings{Sharma2018InsightsOA,
  title={Insights on a putative aminoacyl-tRNA-protein transferase of Leishmania major},
  author={Rohit B. Sharma and Monica Cristina Terr{\~a}o and Felipe Freitas Castro and Reinhard Breitling and Vitor Marcel Faça and Eduardo Brandt de Oliveira and Angela Kaysel Cruz},
  booktitle={PloS one},
  year={2018}
}
The N-end rule pathway leads to regulated proteolysis as an adaptive response to external stress and is ubiquitous from bacteria to mammals. In this study, we investigated a gene coding for a putative core enzyme of this post-translational regulatory pathway in Leishmania major, which may be crucial during cytodifferentiation and the environment adaptive responses of the parasite. Leucyl, phenylalanyl-tRNA protein transferase and arginyl-tRNA protein transferase are key components of this… CONTINUE READING
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