Insights into viral transmission at the uterine-placental interface.

  title={Insights into viral transmission at the uterine-placental interface.},
  author={Lenore Pereira and Ekaterina Maidji and Susan McDonagh and Takako Tabata},
  journal={Trends in microbiology},
  volume={13 4},
During human gestation, viruses can cause intrauterine infections associated with pregnancy complications and fetal abnormalities. The ability of viruses to spread from the infected mother to the fetus arises from the architecture of the placenta, which anchors the fetus to the uterus. Placental cytotrophoblasts differentiate, assume an endothelial phenotype, breach uterine blood vessels and form a hybrid vasculature that amplifies the maternal blood supply for fetal development. Human… CONTINUE READING


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