Insights into thymic aging and regeneration.

@article{Taub2005InsightsIT,
  title={Insights into thymic aging and regeneration.},
  author={Dennis D. Taub and Dan L. Longo},
  journal={Immunological reviews},
  year={2005},
  volume={205},
  pages={72-93}
}
The deterioration of the immune system with progressive aging is believed to contribute to morbidity and mortality in elderly humans due to the increased incidence of infection, autoimmunity, and cancer. Dysregulation of T-cell function is thought to play a critical part in these processes. One of the consequences of an aging immune system is the process termed thymic involution, where the thymus undergoes a progressive reduction in size due to profound changes in its anatomy associated with… CONTINUE READING

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