Insights into thermal resistance of proteins from the intrinsic stability of their alpha-helices.

Abstract

To investigate the role of alpha helices in protein thermostability, we compared energy characteristics of alpha helices from thermophilic and mesophilic proteins belonging to four protein families of known three-dimensional structure, for at least one member of each family. The changes in intrinsic free energy of alpha-helix formation were estimated using… (More)

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@article{Petukhov1997InsightsIT, title={Insights into thermal resistance of proteins from the intrinsic stability of their alpha-helices.}, author={Michael Petukhov and Yong Joo Kil and Sachiko Kuramitsu and Vladislav A. Lanzov}, journal={Proteins}, year={1997}, volume={29 3}, pages={309-20} }