Insights into the role of thromboxane A2 and serotonin in the pathogenesis of unstable angina.

@article{Machado1994InsightsIT,
  title={Insights into the role of thromboxane A2 and serotonin in the pathogenesis of unstable angina.},
  author={Ana Carolina Cabral de Paula Machado and J. A. Aguilar – Saavedra and Cristina Ribeiro},
  journal={Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology},
  year={1994},
  volume={13 12},
  pages={935-46, 893}
}
New research about platelet and endothelial functions is allowing us to better understand the pathogenesis of myocardial ischemic episodes in patients with unstable angina, creating new perspectives for the rational utilization of therapies. In patients with unstable angina, the episodes of symptomatic and silent ischemia are caused by repeated reductions of coronary blood flow. They are the result of the mechanical effect of the growing thrombus, which causes intermittent episodes of partial… CONTINUE READING