Insights into the phylogeny and coding potential of microbial dark matter

  title={Insights into the phylogeny and coding potential of microbial dark matter},
  author={Christian Rinke and Patrick Schwientek and A. Sczyrba and N. Ivanova and I. Anderson and J. Cheng and A. Darling and S. Malfatti and Brandon K Swan and Esther A. Gies and J. Dodsworth and B. Hedlund and G. Tsiamis and S. Sievert and W. Liu and J. Eisen and S. Hallam and N. Kyrpides and R. Stepanauskas and E. Rubin and P. Hugenholtz and T. Woyke},
  • Christian Rinke, Patrick Schwientek, +19 authors T. Woyke
  • Published 2013
  • Biology, Environmental Science, Medicine
  • Nature
  • Genome sequencing enhances our understanding of the biological world by providing blueprints for the evolutionary and functional diversity that shapes the biosphere. However, microbial genomes that are currently available are of limited phylogenetic breadth, owing to our historical inability to cultivate most microorganisms in the laboratory. We apply single-cell genomics to target and sequence 201 uncultivated archaeal and bacterial cells from nine diverse habitats belonging to 29 major mostly… CONTINUE READING

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