Insights into the pathogenesis of hydrocephalus from transgenic and experimental animal models.

@article{Crews2004InsightsIT,
  title={Insights into the pathogenesis of hydrocephalus from transgenic and experimental animal models.},
  author={Leslie A. Crews and Tony Wyss-Coray and Eliezer Masliah},
  journal={Brain pathology},
  year={2004},
  volume={14 3},
  pages={312-6}
}
Hydrocephalus is a progressive brain disorder characterized by abnormalities in the flow of cerebrospinal fluid (CSF) and ventricular dilatation that leads to cerebral atrophy, and if left untreated, can be fatal. Genetic mutations, congenital malformations, infectious diseases, intracerebral hemorrhages and tumors are common conditions resulting in hydrocephalus. Although the causes of obstructive hydrocephalus are better understood, the mechanisms resulting in chronic, progressive… CONTINUE READING
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