Insights into the neurodegenerative process of Alzheimer's disease: a role for mononuclear phagocyte-associated inflammation and neurotoxicity.

@article{Cotter1999InsightsIT,
  title={Insights into the neurodegenerative process of Alzheimer's disease: a role for mononuclear phagocyte-associated inflammation and neurotoxicity.},
  author={Robin L. Cotter and William M. J. Burke and Vince Salazar Thomas and Jane F. Potter and Jialin C Zheng and Howard E. Gendelman},
  journal={Journal of leukocyte biology},
  year={1999},
  volume={65 4},
  pages={416-27}
}
Since the first description of Alzheimer's disease (AD) in 1907, significant progress was made into understanding disease pathophysiology. The enormous effort in AD research has translated into the discovery of genetic linkages for disease, into elucidating the structure and function of the etiologic beta-amyloid protein, and into unraveling the seemingly complex neuroimmunological cascade that affects neuronal dysfunction. Although effective therapies do not currently exist, many are being… CONTINUE READING

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