Insights into the molecular basis of the hormonal control of molting and metamorphosis from Manduca sexta and Drosophila melanogaster.

@article{Riddiford2003InsightsIT,
  title={Insights into the molecular basis of the hormonal control of molting and metamorphosis from Manduca sexta and Drosophila melanogaster.},
  author={Lynn M Riddiford and Kiyoshi Hiruma and Xiaofeng Zhou and Charles A. Nelson},
  journal={Insect biochemistry and molecular biology},
  year={2003},
  volume={33 12},
  pages={
          1327-38
        }
}
This short review summarizes our current knowledge about the role of transcription factors regulated by ecdysteroids and juvenile hormone (JH) in larval molting and metamorphosis in the tobacco hornworm, Manduca sexta, and Drosophila melanogaster. We show new evidence that EcR-A/USP-2 and E75A contribute to the down-regulation of MHR3 after the peak of ecdysteroid. Also, there is suggestive evidence that both MHR4 and betaFTZ-F1 may regulate the expression of dopa decarboxylase as the… CONTINUE READING
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