Insights into the involvement of noncoding RNAs in 5-fluorouracil drug resistance.

Abstract

5-Fluorouracil is a classic chemotherapeutic drug that is widely used to treat various cancers. However, patients often exhibit primary or acquired drug resistance during treatment with 5-fluorouracil chemotherapy. 5-Fluorouracil resistance is a multifactorial event that involves abnormal enzyme metabolism, transport deregulation, cell cycle disorders… (More)
DOI: 10.1177/1010428317697553

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