Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5.

@article{Fricke2008InsightsIT,
  title={Insights into the environmental resistance gene pool from the genome sequence of the multidrug-resistant environmental isolate Escherichia coli SMS-3-5.},
  author={Wolfgang Florian Fricke and Meredith S. Wright and Angela H. Lindell and Derek M. Harkins and Craig Baker-Austin and Jacques Ravel and Ramunas Stepanauskas},
  journal={Journal of bacteriology},
  year={2008},
  volume={190 20},
  pages={6779-94}
}
The increasing occurrence of multidrug-resistant pathogens of clinical and agricultural importance is a global public health concern. While antimicrobial use in human and veterinary medicine is known to contribute to the dissemination of antimicrobial resistance, the impact of microbial communities and mobile resistance genes from the environment in this process is not well understood. Isolated from an industrially polluted aquatic environment, Escherichia coli SMS-3-5 is resistant to a record… CONTINUE READING