Insights into protein folding using physical techniques: studies of lysozyme and alpha-lactalbumin.

Abstract

Understanding the process of protein folding, during which a disordered polypeptide chain is converted into a compact well-defined structure, is one of the major challenges of modern structural biology. In this article we discuss how a combination of physical techniques can provide a structural description of the events which occur during the folding of a… (More)

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