Insights into pediatric diffuse intrinsic pontine glioma through proteomic analysis of cerebrospinal fluid.


Diffuse intrinsic pontine glioma (DIPG) is a leading cause of brain tumor-related death in children. DIPG is not surgically resectable, resulting in a paucity of tissue available for molecular studies. As such, tumor biology is poorly understood, and, currently, there are no effective treatments. In the absence of frozen tumor specimens, body fluids--such… (More)
DOI: 10.1093/neuonc/nos067