Insights into noise modulation in oligomerization systems of increasing complexity.

@article{Pucci2018InsightsIN,
  title={Insights into noise modulation in oligomerization systems of increasing complexity.},
  author={Fabrizio Pucci and Marianne Rooman},
  journal={Physical review. E},
  year={2018},
  volume={98 1-1},
  pages={
          012137
        }
}
Understanding under which conditions the increase of systems complexity is evolutionarily advantageous, and how this trend is related to the modulation of the intrinsic noise, are fascinating issues of utmost importance for synthetic and systems biology. To get insights into these matters, we analyzed a series of chemical reaction networks with different topologies and complexity, described by mass-action kinetics. We showed, analytically and numerically, that the global level of fluctuations… CONTINUE READING
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