Insights into fluorometabolite biosynthesis in Streptomyces cattleya DSM46488 through genome sequence and knockout mutants.

Abstract

Streptomyces cattleya DSM 46488 is unusual in its ability to biosynthesise fluorine containing natural products, where it can produce fluoroacetate and 4-fluorothreonine. The individual enzymes involved in fluorometabolite biosynthesis have already been demonstrated in in vitro investigations. Candidate genes for the individual biosynthetic steps were… (More)
DOI: 10.1016/j.bioorg.2012.06.002

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@article{Zhao2012InsightsIF, title={Insights into fluorometabolite biosynthesis in Streptomyces cattleya DSM46488 through genome sequence and knockout mutants.}, author={Chunhua Zhao and Peng Li and Zixin Deng and Hong-Yu Ou and Ryan P. McGlinchey and David O'Hagan}, journal={Bioorganic chemistry}, year={2012}, volume={44}, pages={1-7} }