Insights into cellular factors that regulate HIV-1 replication in human cells.

Abstract

Retroviruses integrate into the host cell's chromosome. Accordingly, many aspects of the life cycle of retroviruses like HIV-1 are intimately linked to the functions of cellular proteins and RNAs. In this review, we discuss in brief recent genomewide screens for the identification of cellular proteins that assist HIV-1 replication in human cells. We also… (More)
DOI: 10.1021/bi101805f

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3 Figures and Tables