Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-β species.

@article{Hyung2013InsightsIA,
  title={Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-β species.},
  author={Suk-Joon Hyung and Alaina S. DeToma and Jeffrey R. Brender and Sanghyun Lee and Subramanian Vivekanandan and Akiko Kochi and Jung-Suk Choi and Ayyalusamy Ramamoorthy and Brandon T Ruotolo and Mi Hee Lim},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 10},
  pages={3743-8}
}
Despite the significance of Alzheimer's disease, the link between metal-associated amyloid-β (metal-Aβ) and disease etiology remains unclear. To elucidate this relationship, chemical tools capable of specifically targeting and modulating metal-Aβ species are necessary, along with a fundamental understanding of their mechanism at the molecular level. Herein, we investigated and compared the interactions and reactivities of the green tea extract, (-)-epigallocatechin-3-gallate [(2R,3R)-5,7… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 26 times. VIEW TWEETS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 45 extracted citations

Similar Papers

Loading similar papers…