Insights into Pseudomonas putida KT2440 response to phenol‐induced stress by quantitative proteomics

  title={Insights into Pseudomonas putida KT2440 response to phenol‐induced stress by quantitative proteomics},
  author={Pedro Miguel Santos and Dirk Benndorf and Isabel S{\'a}-Correia},
To gain insight into the global mechanism underlying phenol toxicity and tolerance in bacteria, we have generated a two‐dimensional protein reference map and used it to identify variations in protein expression levels in Pseudomonas putida KT2440 following exposure to sub‐lethal inhibitory concentrations of this solvent. Inspection of the two‐dimensional gel electrophoresis gels revealed that 1 h following sudden cell exposure to two different concentrations of phenol, leading to the inhibition… 
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Stress responses of Acinetobacter strain Y during phenol degradation
  • Johnson Lin
  • Biology, Medicine
    Archives of Microbiology
  • 2016
Bacterial strategies of Acinetobacter strain Y via the energy saving mechanisms and the coordinated control between carbon (C)- and nitrogen (N)-limitations in coping with the stress by scavenging the reactive oxygen species are demonstrated.
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The present work will deepen the understanding of metabolism of aromatic compounds in P. putida and may lead to a more comprehensive understanding of solvent tolerance mechanisms in Gram-negative bacteria in general.