Insights into Alzheimer disease pathogenesis from studies in transgenic animal models

@inproceedings{Schaeffer2011InsightsIA,
  title={Insights into Alzheimer disease pathogenesis from studies in transgenic animal models},
  author={Evelin Lisete Schaeffer and Micheli Figueir{\'o} and Wagner F. Gattaz},
  booktitle={Clinics},
  year={2011}
}
Alzheimer disease is the most common cause of dementia among the elderly, accounting for ~60-70% of all cases of dementia. The neuropathological hallmarks of Alzheimer disease are senile plaques (mainly containing p-amyloid peptide derived from amyloid precursor protein) and neurofibrillary tangles (containing hyperphosphorylated Tau protein), along with neuronal loss. At present there is no effective treatment for Alzheimer disease. Given the prevalence and poor prognosis of the disease, the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 106 references

Similar Papers

Loading similar papers…