Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.

@article{Stinear2008InsightsFT,
  title={Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.},
  author={Timothy P Stinear and Torsten Seemann and Paul F Harrison and Grant A. Jenkin and John K. Davies and Paul D R Johnson and Zahra Abdellah and Claire Arrowsmith and Tracey Chillingworth and Carol M Churcher and Kay Clarke and Ann Cronin and Paul Davis and I Goodhead and Nancy Holroyd and Kay Jagels and Angela Lord and Sharon Moule and Karen Mungall and Halina T Norbertczak and Michael A. Quail and Ester Rabbinowitsch and Danielle L Walker and Brian White and Sally Whitehead and Pamela Long Claus Small and Roland Brosch and L. Ramakrishnan and Michael A. Fischbach and Julian Parkhill and Stewart T Cole},
  journal={Genome research},
  year={2008},
  volume={18 5},
  pages={729-41}
}
Mycobacterium marinum, a ubiquitous pathogen of fish and amphibia, is a near relative of Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of the M strain of M. marinum comprises a 6,636,827-bp circular chromosome with 5424 CDS, 10 prophages, and a 23-kb mercury-resistance plasmid. Prominent features are the very large number of genes (57) encoding polyketide synthases (PKSs) and nonribosomal peptide synthases (NRPSs) and the most extensive repertoire yet… CONTINUE READING